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Findings have also shown that some food types such as the Western diet have higher quantities of TMA precursor levels consequently altering TMAO levels in the long term [111]

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In this large, real-world, propensity scorematched analysis, semaglutide was associated with significantly lower risks of all-cause death, acute myocardial infarction, stroke, and acute heart failure compared with dulaglutide

Side effects tend to be more common and intense in the first weeks of taking a semaglutide or other GLP-1, but nausea can last for several weeks up to a few months